Study
Colorectal cancer cells possess an equipotent capacity to enter a developmental pausing-like state to survive chemotherapy
Study ID | Alternative Stable ID | Type |
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EGAS00001004773 | Cancer Genomics |
Study Description
Study Datasets 2 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
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EGAD00001006847 |
NA
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Illumina HiSeq 2500 | 12 |
EGAD00001006849 |
Cancer cells enter a reversible drug tolerant persister (DTP) state to evade death from both chemotherapies and targeted agents. It is increasingly appreciated that the DTP state is an important driver of therapy failure and tumor relapse. We combined cellular barcoding and mathematical modeling in patient-derived colorectal cancer xenograft models to identify and characterize the cancer cells capable of generating DTPs in response to standard-of-care chemotherapy. Barcode analysis revealed no ... (Show More)
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Illumina HiSeq 2500 | 12 |
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