ENCORE__New_Targets_for_Effective_Combination_Therapies_in_Tumors_with_Unmet_Medical_Need

This study utilises 2G-CRISPR screens to identify effective target combinations in KRAS-mutant colorectal and triple-negative breast cancer cell lines.

Type: Cancer Genomics
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001015754	Raw sgRNA sequencing data from a pilot CRISPR screening library to test the dual guide vector system (8,914 guide pairs), and from a large scale genetic interaction screen (~100,136 guide pairs) in HT-29 cells. This data refers to Burgold et al. Nature Communications 2025.	Illumina HiSeq 2500 Illumina MiSeq	1