Study
Cell of Origin and Early Evolution of Leukemia in Down Syndrome
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001004780 | Other |
Study Description
Study Datasets 1 dataset.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001006555 |
To investigate the mechanism by which GATA1s and STAG2 deficiency contribute to Down Syndrome leukemogenesis, specifically within the propagating CD34/CD117 cell fractions from primary xenografts, we carried out transcriptional and epigenetic profiling by RNAseq and ATACseq. The chromatin accessibility landscape was compared to bulk ATACseq of
individually sorted N-FL HSPC subpopulations.
To investigate the mechanism underlying the synergy between T21 and GATA1s in driving preleukemia ... (Show More)
|
Illumina HiSeq 2500,NextSeq 500 | 91 |
Who archives the data?
