Study

Targeted sequencing DDR genes in cancer stem cells

Study ID Alternative Stable ID Type
EGAS00001004892 Other

Study Description

Colorectal cancer stem cells (CSCs) show heterogeneous levels of constitutive replication stress leading distinct dependence on the replication stress response. The aim of the projects was to find genetic, epigenetic, phenotypic factors associated with the resistance of colorectal CSCs to inhibitors of the ATR/CHK1 pathway, which regulates of the replication stress response. Different pairs of colorectal CSCs sensitive and resistant to ATR or CHK1 inhibitors were analyzed

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
EGAD00001006774
CSC DDR dataset contains 4 bam files of two pairs of colorectal CSCs sensitive and resistant to ATR or CHK1 inhibitor
NextSeq 500 1

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