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Finding structural variation and functional consequences from the primary leukemia cells (AML) at the single-cell level

In this study, we aimed to identify somatic structural variation of acute myeloid leukemia (AML) at the single-cell level and investigate its direct consequence on the nucleosome occupancy using scNOVA approach. For this purpose, we performed strand-specific single-cell sequencing of primary leukemia samples from 32 year old male donor.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001006782 NextSeq 500 42
Publications Citations
Functional analysis of structural variants in single cells using Strand-seq.
Nat Biotechnol 41: 2023 832-844