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Oncolytic virotherapy mediated anti-tumor response in primary cutaneous B-cell lymphoma: a single-cell perspective

Type: RNASeq
Archiver: European Genome-phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001006829	We are presenting raw and processed data of our study where we analyze fine-needle aspirate (FNA) samples of primary cutaneous B-cell lymphoma patients undergoing oncolytic virotherapy (https://clinicaltrials.gov/ct2/show/NCT03458117). We are uploading single cell RNA-sequencing and immune repertoire profiling data of 29 FNA samples from four pCBCL patients. The four patients have three different subtypes of primary cutaneous B-cell lymphoma: pCDLBCL-LT, pCFCL and pCMZL. The samples are taken at different time points following T-VEC injection (from baseline up to 91 days after injection). We are uploading the sequences in BAM format and the outputs of the cellranger pipeline (count matrices and filtered VDJ contigs) in CSV format.	NextSeq 500	34

Publications	Citations
Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation. Griss J, Gansberger S, Oyarzun I, Simon M, Drach MC, Nguyen V, Shaw LE, Mann U, Porkert S, Farlik M, Weninger W, Dolak W, Aschenbrenner B, Lichtenberger BM, Ziegler-Santos S, Wagner C, Simonitsch-Klupp I, Wagner SN, Jonak C, Brunner PM. Nat Commun 17: 2026 2366	0