The Genetic History of Greenlandic-European contact

The Inuit ancestors of the Greenlandic people arrived in Greenland close to 1000 years ago. Since then, Europeans from many different countries have been present in Greenland. Consequently, the present-day Greenlandic population has ~25% of its genetic ancestry from Europe. In this study, we investigated to what extent different European countries have contributed to this genetic ancestry.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 4 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00010002057	This file fileset has 4607 Greenlanders scored on the Illumina MEGA array (1,622,813 sites), and has been put on the plus strand. The data is in PLINK bed/bim/fam format. The Greenlandic individuals originate from two population surveys, B99 and IHIT.	Illumina MEGA array	4607

Publications	Citations
The genetic history of Greenlandic-European contact. Waples RK, Hauptmann AL, Seiding I, Jørsboe E, Jørgensen ME, Grarup N, Andersen MK, Larsen CVL, Bjerregaard P, Hellenthal G, Hansen T, Albrechtsen A, Moltke I. Curr Biol 31: 2021 2214-2219.e4	8
A novel splice-affecting <i>HNF1A</i> variant with large population impact on diabetes in Greenland. Thuesen ACB, Stæger FF, Kaci A, Solheim MH, Aukrust I, Jørsboe E, Santander CG, Andersen MK, Li Z, Gilly A, Stinson SE, Gjesing AP, Bjerregaard P, Pedersen ML, Larsen CVL, Grarup N, Jørgensen ME, Zeggini E, Bjørkhaug L, Njølstad PR, Albrechtsen A, Moltke I, Hansen T. Lancet Reg Health Eur 24: 2023 100529	5
GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal. Senftleber NK, Andersen MK, Jørsboe E, Stæger FF, Nøhr AK, Garcia-Erill G, Meisner J, Santander CG, Balboa RF, Gilly A, Bjerregaard P, Larsen CVL, Grarup N, Jørgensen ME, Zeggini E, Moltke I, Hansen T, Albrechtsen A. Eur J Hum Genet 32: 2024 215-223	2
Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans. Lin L, Andersen MK, Stæger FF, Li Z, Hanghøj K, Linneberg A, Grarup N, Jørgensen ME, Hansen T, Moltke I, Albrechtsen A. Genome Med 16: 2024 71	0