Study

The genomic landscape of childhood acute lymphoblastic leukaemia with intrachromosomal amplification of chromosome 21 (iAMP21-ALL)

Study ID Alternative Stable ID Type
EGAS00001004998 Other

Study Description

Intrachromosomal amplification of chromosome 21 (iAMP21) results from breakage-fusion-bridge cycles and chromothripsis defines a cytogenetic subgroup of childhood B-cell precursor acute lymphoblastic leukemia (B-ALL) cases associated with a poor prognosis. To systematically characterize the mechanism of somatic alternations in iAMP21, we perform integrated genomic, cytogenetic and transcriptomic analysis of 128 cases.

Study Datasets 2 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001006954
iAMP21 WGS, total of 224 samples
HiSeq X Ten,Illumina HiSeq 2500,Illumina NovaSeq 6000 224
EGAD00001007577
RNAseq samples from the iAMP21 study
Illumina HiSeq 2500,Illumina HiSeq 4000,NextSeq 550 88

Who archives the data?

There are no publications available