Bone marrow derived stromal cells from Myelodysplastic Syndromes

Study

Study ID	Alternative Stable ID	Type
EGAS00001005051		Other

Study Description

In this study we performed exome sequencing of bone marrow derived, in-vitro expanded mesenchymal stromal cells from patients with Myelodysplastic Syndromes in order to assess clonal mutations in the non hematopoietic compartment. We used bone marrow mononuclear cells as germline controls. Validation was carried out with amplicon based resequencing. Alongside we provide RNA Sequencing of MDS and healthy MSCs.

Study Datasets 2 datasets.

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Dataset ID	Description	Technology	Samples
EGAD00001006968	bam files, mapped to hg19 after dedup, recal, recalibration and clipping of overlapping redas bam files, mapped to hg19 after dedup, recal, recalibration and clipping of overlapping redas	Illumina HiSeq 4000,Illumina MiSeq,Illumina NovaSeq 6000	210
EGAD00001007760	This dataset contains bam files mapped to hg19 that either were primary bone marrow cells or sorted human cells after long term engraftment in NSG mice. This dataset contains bam files mapped to hg19 that either were primary bone marrow cells or sorted human cells after long term engraftment in NSG mice.	Illumina NovaSeq 6000	229

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