Breast tissue methylation analysis - EGA European Genome-Phenome Archive

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00010002073	Raw methylation from breast biopsies in BRCA mutation carriers or controls before and after 3 months of preventive mifepristone treatment.	Illumina MethylationEPIC Array	77
EGAD00010002074	Raw methylation data from normal breast tissue adjacent to a malignancy (TNBC)	Illumina MethylationEPIC Array	14
EGAD00010002075	Raw methylation data from breast tissue collected during risk-reducing surgery in BRCA1/2 mutation carriers.	Illumina MethylationEPIC Array	14
EGAD00010002076	Raw methylation data from normal breast tissue.	Illumina MethylationEPIC Array	14
EGAD00010002077	Raw methylation data from triple negative breast cancer.	Illumina MethylationEPIC Array	14

Publications	Citations
The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples. Barrett JE, Herzog C, Jones A, Leavy OC, Evans I, Knapp S, Reisel D, Nazarenko T, Kim YN, Franchi D, Ryan A, Franks J, Bjørge L, Zikan M, Cibula D, Harbeck N, Colombo N, Dudbridge F, Jones L, Sundström K, Dillner J, Rådestad AF, Gemzell-Danielsson K, Pashayan N, Widschwendter M. Nat Commun 13: 2022 449	28
Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock. Barrett JE, Herzog C, Kim YN, Bartlett TE, Jones A, Evans I, Cibula D, Zikan M, Bjørge L, Harbeck N, Colombo N, Howell SJ, Rådestad AF, Gemzell-Danielsson K, Widschwendter M. Genome Biol 23: 2022 52	10
Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women. Bartlett TE, Evans I, Jones A, Barrett JE, Haran S, Reisel D, Papaikonomou K, Jones L, Herzog C, Pashayan N, Simões BM, Clarke RB, Evans DG, Ghezelayagh TS, Ponandai-Srinivasan S, Boggavarapu NR, Lalitkumar PG, Howell SJ, Risques RA, Rådestad AF, Dubeau L, Gemzell-Danielsson K, Widschwendter M. Genome Med 14: 2022 64	16
Validation of blood-based detection of breast cancer highlights importance for cross-population validation. Theeuwes B, Ambatipudi S, Herceg Z, Herzog CM, Widschwendter M. Nat Commun 16: 2025 2164	1
Systems epigenetic approach towards non-invasive breast cancer detection. Herzog CMS, Theeuwes B, Jones A, Evans I, Bjørge L, Zikan M, Cibula D, Harbeck N, Colombo N, Pashayan N, Widschwendter M. Nat Commun 16: 2025 3082	2
Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer. Herzog CMS, Redl E, Barrett J, Aminzadeh-Gohari S, Weber DD, Tevini J, Lang R, Kofler B, Widschwendter M. Commun Med (Lond) 5: 2025 98	1