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Transcriptome sequencing of hepatocellular carcinoma biopsies (proteogenomic study)

We performed a proteogenomic analysis of hepatocellular carcinomas (HCCs) across clinical stages and etiologies to define the deregulated pathways and heterogeneity among HCCs. We identified pathways that are differentially regulated on the genomic, transcriptomic, proteomic and phosphoproteomic levels. Integrative clustering identified HCC subgroups that show distinct regulation of biological processes, metabolic reprogramming and kinase activation.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001008205 Illumina HiSeq 2500 137
Publications Citations
Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages.
Nat Commun 13: 2022 2436
28
Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model.
PLoS Comput Biol 18: 2022 e1009767
2