Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia
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Blast crisis (BC) predicts dismal outcomes in patients with chronic myeloid leukaemia (CML). We comprehensively investigated genetic abnormalities in 136 BC and 148 chronic phase (CP) samples obtained from 216 CML patients using exome and targeted sequencing.
Study Datasets 1 dataset.
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Whole exome sequencing of 52 chronic phase/blast crisis pairs obtained from chronic myeloid leukemia
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