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Profiling of H3K27ac landscape in immune cells from rheumatoid arthritis patients and healthy controls

We collected peripheral blood mononuclear cells (PBMC) from 6 RA patients and 4 healthy controls, as well as synovial fluid from the same RA patients. We then sorted B cells, CD4+ and CD8+ T cells, regulatory T cells and monocytes using flow cytometry and profiled regions marked with H3K27ac using CUT&Tag.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001007003 Illumina MiSeq 59
Publications Citations
The impact of cell type and context-dependent regulatory variants on human immune traits.
Genome Biol 22: 2021 122
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