Study
Platelet response in aspirin adherent pregnant women
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001005188 | Other |
Study Description
We conducted an unbiased genome-wide assessment of genomic factors that may influence response to low-dose aspirin in pregnant women at high risk of pre-eclampsia in two pregnancy cohorts: Liverpool (n=91) and Dublin (n=91). We applied UK Axiom microarray technology for GWAS investigations. We specified tight phenotyping with COX-selective urinary 11-dehydrothromboxane B2 (pg/mg creatinine) and accounted for adherence/platelet exposure to aspirin by detection of aspirin’s principal urinary metabolite, SUA, with nuclear magnetic resonance (NMR).
Study Datasets 2 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00010002093 |
Dublin Aspirin platelet response genomics cohort
|
UK Biobank Axiom array | 91 |
| EGAD00010002094 |
Liverpool Aspirin platelet response genomics cohort
|
UK Biobank Axiom array | 91 |
Who archives the data?
