Study

Characterizing microbiome-directed fibre snacks in gnotobiotic mice and humans

Study ID Alternative Stable ID Type
EGAS00001005268 Other

Study Description

Knowledge of the interrelationships between what we eat and the configurations of our gut microbial communities is providing important insights into how food components that are not directly metabolized by human enzymes are linked to our physiology and health status. Changing food preferences brought about by Westernization that have deleterious health effects1,2, plus rapid population expansion, ongoing challenges to sustainable agriculture, and other forces contributing to increased food insecurity, are catalyzing efforts to identify more nutritious and affordable foods3. The gut microbial community is complex, dynamic, and exhibits considerable intra- and interpersonal variation in its composition and functions. The massive number of potential interactions between its components makes it challenging to define the mechanisms by which food ingredients affect community properties. There is also a paucity of information about the ‘bioactive’ ingredients of foods that influence the fitness and expressed functions of community members. Here, plant fibres, from different sustainable ... (Show More)

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
EGAD00010002132
SOMAscan plasma proteome datasets generated from participants consuming the fiber blend snack prototype (study 2)
SOMAscan 1.3K Proteomic Assay 70
EGAD00010002133
SOMAscan plasma proteome datasets generated from participants consuming the pea fibre snack prototype (study 1)
SOMAscan 1.3K Proteomic Assay 72

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