Human Inflammatory Skin Disease scRNA-seq - EGA European Genome-Phenome Archive

Dataset ID	Description	Technology	Samples
EGAD00001008624	This dataset includes 10X Genomics 3' single cell-RNA-seq profiles from 24 human rashes and 7 healthy controls. BAM files are provided for each sample.	Illumina HiSeq 4000	31

Publications	Citations
Classification of human chronic inflammatory skin disease based on single-cell immune profiling. Liu Y, Wang H, Taylor M, Cook C, Martínez-Berdeja A, North JP, Harirchian P, Hailer AA, Zhao Z, Ghadially R, Ricardo-Gonzalez RR, Grekin RC, Mauro TM, Kim E, Choi J, Purdom E, Cho RJ, Cheng JB. Sci Immunol 7: 2022 eabl9165	108
Defining Patient-Level Molecular Heterogeneity in Psoriasis Vulgaris Based on Single-Cell Transcriptomics. Liu Y, Wang H, Cook C, Taylor MA, North JP, Hailer A, Shou Y, Sadik A, Kim E, Purdom E, Cheng JB, Cho RJ. Front Immunol 13: 2022 842651	14
Isolation of human cutaneous immune cells for single-cell RNA sequencing. Hailer AA, Wu D, El Kurdi A, Yuan M, Cho RJ, Cheng JB. STAR Protoc 4: 2023 102239	4
GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing. Yu DM, Zhao J, Lee EE, Kim D, Mahapatra R, Rose EK, Zhou Z, Hosler C, El Kurdi A, Choe JY, Abel ED, Hoxhaj G, Westover KD, Cho RJ, Cheng JB, Wang RC. J Clin Invest 133: 2023 e170706	37
Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis. Singh TP, Farias Amorim C, Lovins VM, Bradley CW, Carvalho LP, Carvalho EM, Grice EA, Scott P. J Exp Med 220: 2023 e20230558	16
Immunological profile of lactate metabolism-related genes in Psoriasis a comprehensive analysis based on bulk and single-cell RNA sequencing data. Liu SY, Lv J, Li F, Zhang YX. Sci Rep 15: 2025 6872	1
Detection by Single-Cell RNA Sequencing of Virally Mediated Skin Diseases. Zhou L, Leung TH. JID Innov 5: 2025 100348	1
TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells. Arroyo Hornero R, Maqueda-Alfaro RA, Solís-Barbosa MA, Leylek RA, Medina Chavez O, Martinez OM, Gottfried-Blackmore A, Idoyaga J. Nat Immunol 26: 2025 1540-1552	13
CD64 binding potential does not translate into enhanced therapeutic efficacy for anti-IL-23 antibodies under physiologically relevant conditions. Cohen-Solal JF, Pohl CS, Cummings SM, Gygi JP, Safikhani Z, Bartocha B, Buckley CD, Dong Y, Eyerich K, Karsen SD, Lynch GR, Macoritto M, Morisset PA, Nelson OD, Radstake T, Rieder F, Rivas J, Savaryn JP, Smith KM, Stulir M, Szynal C, Tylek C, Veldman GM, Wasserman LG, Westmoreland S, Chaudhary N, Staron MM. Mol Med 32: 2026 70	0