Molecular profiles and urinary biomarkers of upper tract urothelial carcinomas associated with aristolochic acid exposure

Study

Study ID	Alternative Stable ID	Type
EGAS00001005363		Other

Study Description

This study present a molecular analysis of upper urinary tract urothelial tumours (UTUC) and urines of patients with past exposure to carcinogenic aristolochic acid (AA). Tumor exome and transcriptome sequencing revealed the AA-specific mutations in UTUC and identified deleterious mutations at both the gene and transcript levels.

Study Datasets 2 datasets.

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Dataset ID	Description	Technology	Samples
EGAD00001008137	This dataset includes mutation profiling by Whole-exome sequencing of 3 upper urinary tract urothelial tumours (UTUC). This dataset includes mutation profiling by Whole-exome sequencing of 3 upper urinary tract urothelial tumours (UTUC).	Illumina HiSeq 2000	6
EGAD00001008138	This dataset includes transcription profiling by RNA-seq of 3 upper urinary tract urothelial tumours (UTUC). This dataset includes transcription profiling by RNA-seq of 3 upper urinary tract urothelial tumours (UTUC).	Illumina HiSeq 2000	3

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