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Single cell copy number and chromatin accessibility in primary multiple myeloma cells

Multiple myeloma is characterized by inter- and intra-clonal heterogeneity. We have used single cell profiling of the genome (scCNV) and epigenome (csATAC) of clonal plasma cells to delineate the clonal heterogeneity in serially collected samples.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001007788 Illumina NovaSeq 6000 NextSeq 500 10
Publications Citations
Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer.
Sci Adv 7: 2021 eabg6045