Single cell copy number and chromatin accessibility in primary multiple myeloma cells
Multiple myeloma is characterized by inter- and intra-clonal heterogeneity. We have used single cell profiling of the genome (scCNV) and epigenome (csATAC) of clonal plasma cells to delineate the clonal heterogeneity in serially collected samples.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
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|Illumina NovaSeq 6000 NextSeq 500
Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer.
Sci Adv 7: 2021 eabg6045