Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states

1 Dataset 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001009694	We profiled CD45- enriched, viable cells from GBM (n = 7) and IDH-MUT (n = 7) primary samples with multi-modality single-cell sequencing of scDNAme (by reduced representation bisulfite sequencing [RRBS]) and scRNAseq (Smart-seq2).	Illumina HiSeq 2500 Illumina NovaSeq 6000	2989

Publications	Citations
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states. Chaligne R, Gaiti F, Silverbush D, Schiffman JS, Weisman HR, Kluegel L, Gritsch S, Deochand SD, Gonzalez Castro LN, Richman AR, Klughammer J, Biancalani T, Muus C, Sheridan C, Alonso A, Izzo F, Park J, Rozenblatt-Rosen O, Regev A, Suvà ML, Landau DA. Nat Genet 53: 2021 1469-1479	91
RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma. Song X, Tiek D, Miki S, Huang T, Lu M, Goenka A, Iglesia R, Yu X, Wu R, Walker M, Zeng C, Shah H, Weng SHS, Huff A, Zhang W, Koga T, Hubert C, Horbinski CM, Furnari FB, Hu B, Cheng SY. J Clin Invest 134: 2024 e173789	2