Minor intron splicing efficiency increases with the development of lethal prostate cancer

2 Datasets 1 Publication

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Dataset ID	Description	Technology	Samples
EGAD00001007996	scRNAseq data of scrambled and siRNA-mediated knock-down (96h) of the minor spliceosome snRNA U6atac in androgen-sensitive LNCaP cells and in patient derived neuroendocrine organoids (PM154). Three replicates for each cell line.	Illumina NovaSeq 6000	12
EGAD00001008034	Bulk RNAseq data of scrambled and siRNA-mediated knock-down of the minor spliceosome snRNA U6atac in androgen-sensitive LNCaP cells (L), androgen-insensitive C4-2 (C) and 22Rv1 (R) cells and in patient derived neuroendocrine organoids PM154 (P).	Illumina NovaSeq 6000	32

Publications	Citations
Minor intron splicing is critical for survival of lethal prostate cancer. Augspach A, Drake KD, Roma L, Qian E, Lee SR, Clarke D, Kumar S, Jaquet M, Gallon J, Bolis M, Triscott J, Galván JA, Chen Y, Thalmann GN, Kruithof-de Julio M, Theurillat JP, Wuchty S, Gerstein M, Piscuoglio S, Kanadia RN, Rubin MA. Mol Cell 83: 2023 1983-2002.e11	6