Application of Hi-C sequencing to detect structural variants in B-cell acute lymphoblastic leukemia

Study ID Alternative Stable ID Type
EGAS00001005605 Other

Study Description

Large structural variants are easily detected by Hi-C sequencing as strong, distant signals on a Hi-C contact map. Translocations are frequently evident in B-ALL and accurate identification of these translocations can guide clinical treatment options. Here were apply shallow Hi-C sequencing as an unbiased, cost-effective approach to identify translocations among B-ALL patients.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
Hi-C sequencing data includes 5 samples collected from 4 B-ALL patients.
NextSeq 500 5

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