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ADAPTeR Study: scRNA and scTCR data from TILs from two ccRCC patients treated with anti-PD1

TILs were extracted from two ccRCC patients treated with (Nivolumab) anti-PD1, one was responsive to treatment, the other non-responsive. IgG4 staining was used to separate cells into anti-PD1 bound and unbound, the samples then underwent paired scRNA and scTCR sequencing on the 10x Genomics platform.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001008166 NextSeq 550 64
Publications Citations
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell 39: 2021 1497-1518.e11