Study

Human and rat skeletal muscle multi-omic profiling

Study ID Alternative Stable ID Type
EGAS00001005730 Other

Study Description

Skeletal muscle accounts for the largest proportion of human body mass, on average, and is a key tissue in complex diseases and mobility. It is composed of several different cell and muscle fiber types. Here, we optimize single-nucleus ATAC-seq (snATAC-seq) to map skeletal muscle cell-specific chromatin accessibility landscapes in frozen human and rat samples, and single-nucleus RNA-seq (snRNA-seq) to map cell-specific transcriptomes in human. We additionally perform multi-omics profiling (gene expression and chromatin accessibility) on human and rat muscle samples.

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
EGAD00001008323
Illumina sequencing data (fastq files) representing single-nucleus (sn) ATAC-seq, snRNA-seq, bulk ATAC-seq, and snATACseq+snRNAseq multiomics data from human and rat skeletal muscle samples (19 libraries total). Includes a README file that describes the relationship between libraries, samples, and files.
Illumina NovaSeq 6000 15
EGAD00010002248
Genotypes for 2 human skeletal muscle samples
Illumina Infinium multi-ethnic global-8 v1 kit 2

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