Human and rat skeletal muscle multi-omic profiling

Study ID Alternative Stable ID Type
EGAS00001005730 Other

Study Description

Skeletal muscle accounts for the largest proportion of human body mass, on average, and is a key tissue in complex diseases and mobility. It is composed of several different cell and muscle fiber types. Here, we optimize single-nucleus ATAC-seq (snATAC-seq) to map skeletal muscle cell-specific chromatin accessibility landscapes in frozen human and rat samples, and single-nucleus RNA-seq (snRNA-seq) to map cell-specific transcriptomes in human. We additionally perform multi-omics profiling (gene expression and chromatin accessibility) on human and rat muscle samples.

Study Datasets 2 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
Illumina sequencing data (fastq files) representing single-nucleus (sn) ATAC-seq, snRNA-seq, bulk ATAC-seq, and snATACseq+snRNAseq multiomics data from human and rat skeletal muscle samples (19 libraries total). Includes a README file that describes the relationship between libraries, samples, and files.
Illumina NovaSeq 6000 15
Genotypes for 2 human skeletal muscle samples
Illumina Infinium multi-ethnic global-8 v1 kit 2

Who archives the data?