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Amplified EPOR/JAK2 genes define a unique subtype of acute erythroid leukemia

Acute erythroid leukemia (AEL) is a unique subtype of acute myeloid leukemia characterized by prominent erythroid proliferation, whose molecular basis is poorly understood. To elucidate the underlying mechanism of erythroid proliferation, we performed comprehensive genomic study. The aim of this study is to unveil genotype phenotype correlations and the feasible molecular targets for therapy of AEL.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001008357 Illumina HiSeq 2500 40
Publications Citations
Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia.
Blood Cancer Discov 3: 2022 410-427