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DNA sequencing for human normal endometrial glands

To elucidate the timing and mechanism of the clonal expansion of somatic mutations in cancer-associated genes in the normal endometrium, we conducted whole-exome and whole-genome sequencing for 56 endometrial glands and matched blood samples from 4 women. By collecting endometrial glands from different parts of the endometrium, we showed that multiple glands with the same somatic mutations occupied substantial areas of the endometrium.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001008377 Illumina NovaSeq 6000 60
Publications Citations
Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium.
Nat Commun 13: 2022 943