SPECTA RP-1759-AYA Sarcoma cohort

EORTC-SPECTA RP1759 study focuses on cancers in adolescent and young adult (AYA), age 12 to 29 years. This study explicitly recruited AYA patients and therefore collected empirical data to bridge the molecular gap between pediatric and adult oncology. The initial pilot study, activated in February 2019 across Europe, aimed to recruit 100 AYA patients (aged 12-29 years) with newly diagnosed or relapsed high-grade gliomas and high-grade bone and soft tissue sarcomas. The primary objective of the pilot is to determine feasibility and recruitment rates. Here we submit the data from patients with newly diagnosed, recurrent intermediate or high-grade sarcoma that were collected and analyzed during the study. More specifically, we submit raw FASTQ files obtained from whole exome sequencing (WES) of matching tumor and blood samples, tumor RNA sequencing and DNA methylation profiling.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

4 Datasets

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001008393	Raw FASTQ files obtained by RNA sequencing of tumor samples from patients (age 12-29) with newly diagnosed, recurrent intermediate or high-grade sarcoma.	Illumina HiSeq 4000	26
EGAD00001008394	Raw FASTQ files obtained from whole exome sequencing (WES) of tumor samples from patients with newly diagnosed, recurrent intermediate or high-grade sarcoma.	Illumina HiSeq 4000	51
EGAD00001008405	Raw FASTQ files obtained from whole exome sequencing (WES) of normal samples from patients with newly diagnosed, recurrent intermediate or high-grade sarcoma.	Illumina HiSeq 4000	1
EGAD00010002275	Raw methylation array data for tumor samples from patients with newly diagnosed, recurrent intermediate or high-grade sarcoma.	Illumina MethylationEPIC BeadChip Array	48