Mapping genetic effects on cell type-specific chromatin accessibility using single nucleus ATAC-seq
|Study ID||Alternative Stable ID||Type|
Gene regulation is highly cell type-specific and understanding the function of non-coding genetic variants associated with complex traits requires molecular phenotyping at cell type resolution. In this study we performed single nucleus ATAC-seq (snATAC-seq) and genotyping in peripheral blood mononuclear cells from 13 individuals. We mapped chromatin accessibility QTLs (caQTLs) in each immune cell type and sub-type in a subset of 10 samples of European genetic ancestry.
Study Datasets 1 dataset.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Combined genotyping files from 13 PBMC samples
|illumina Infinium Omni2.5-8||13|