Single cell genomic variation induced by mutational processes in cancer

How cell-to-cell copy number alterations that underpin genomic instability in human cancers drive genomic and phenotypic variation, and consequently cancer evolution, remains understudied. Here, applying scaled single cell whole genome sequencing to wildtype, TP53-deficient and TP53/BRCA1/2-deficient mammary epithelial cells (n=13,818 genomes) and primary triple negative breast (TNBC) and high grade serous ovarian cancers (HGSC) (n=22,057 genomes), we identified three distinct ‘foreground’ mutational patterns defined by cell-to-cell copy number and structural variation properties occurring in the ‘background’ of cancer-associated genomic instability. Cell and clone-specific high level amplifications (HLAMPs), parallel allele-specific copy number alterations and copy number segment length variation (serrate structural variations) exhibited measurable phenotypic and evolutionary consequences. Clone-specific HLAMPs in known oncogenes were highly prevalent in fold back inversion (FBI)-bearing tumors and associated with increased clone-to-clone phenotypic variation in gene expression inferred from matched single cell RNASeq. Parallel allele-specific alterations were linked with phylogenetically determined evolutionary diversity and clone-specific mono-allelic expression. Serrate patterns present across all clones were increased in FBI tumors, most prominently on a tetraploid background and were highly correlated with increased genomic diversity of cellular populations. Taken together, we show that cell-to-cell structural-copy number variation significantly impacts the phenotypes and evolutionary diversity of TNBC and HGSC, revealing previously hidden genomic states of cancer cells.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

361 Datasets 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001009111	10x Genomics Single Cell Gene Expression for Telomerase immortalized breast epithelium cell line 184-hTERT-22 L9 112.109	Illumina HiSeq 2500	1
EGAD00001009112	10x Genomics Single Cell Gene Expression for Telomerase immortalized breast epithelium cell line 184-hTERT-22 L9 116.126	Illumina HiSeq 2500	1
EGAD00001009113	10x Genomics Single Cell Gene Expression for Telomerase immortalized breast epithelium cell line 184-hTERT-22 L9 83.86	Illumina HiSeq 2500	1
EGAD00001009114	10x Genomics Single Cell Gene Expression for Telomerase immortalized breast epithelium cell line 184-hTert L9 116.66	Illumina HiSeq 2500	1
EGAD00001009115	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 4	BGISEQ-500	1
EGAD00001009116	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 6	Illumina HiSeq 2500	1
EGAD00001009117	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA604 passage 6	Illumina HiSeq 2500	1
EGAD00001009118	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA604 passage 8	Illumina HiSeq 2500	1
EGAD00001009119	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA604 passage 7	NextSeq 500	1
EGAD00001009120	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA609 passage 6	Illumina HiSeq 2500	1
EGAD00001009121	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1049 passage 1	NextSeq 500	1
EGAD00001009122	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1052 passage 1	NextSeq 500	1
EGAD00001009123	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1053 passage 1	NextSeq 500	1
EGAD00001009124	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1051 passage 1	NextSeq 500	1
EGAD00001009125	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1050 passage 1	NextSeq 500	1
EGAD00001009126	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1050 passage 1	NextSeq 500	1
EGAD00001009127	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1052 passage 1	NextSeq 500	1
EGAD00001009128	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1053 passage 1	Illumina HiSeq 2500	1
EGAD00001009129	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1093 passage 1	NextSeq 500	1
EGAD00001009130	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1091 passage 1	NextSeq 500	1
EGAD00001009131	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1053 passage 1	NextSeq 500	1
EGAD00001009132	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1096 passage 1	NextSeq 500	1
EGAD00001009133	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1051 passage 1	HiSeq X Ten	1
EGAD00001009134	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1052 passage 1	HiSeq X Ten	1
EGAD00001009135	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1181 passage 1	Illumina HiSeq 2500	1
EGAD00001009136	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1096 passage 1	Illumina HiSeq 2500	1
EGAD00001009137	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1096 passage 1	Illumina HiSeq 2500	1
EGAD00001009138	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1162 passage 1	Illumina HiSeq 2500	1
EGAD00001009139	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient SA1096	NextSeq 500	1
EGAD00001009140	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1049 passage 1	NextSeq 500	1
EGAD00001009141	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1050 passage 1	Illumina HiSeq 2500	1
EGAD00001009142	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA605 passage 3	NextSeq 500	1
EGAD00001009143	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma cell line OV2295	HiSeq X Ten	1
EGAD00001009144	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma cell line OV2295(R2)	HiSeq X Ten	1
EGAD00001009145	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient SA1184	NextSeq 500	1
EGAD00001009146	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma patient-derived xenograft SA1047 passage 1	HiSeq X Ten	1
EGAD00001009147	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 4	Illumina HiSeq 2500	1
EGAD00001009148	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 8	NextSeq 500	1
EGAD00001009149	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 6	BGISEQ-500	1
EGAD00001009150	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 6	Illumina HiSeq 2500	1
EGAD00001009151	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 7	HiSeq X Ten	1
EGAD00001009152	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 4	BGISEQ-500	1
EGAD00001009153	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 5	Illumina HiSeq 2500	1
EGAD00001009154	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA1035 passage 6	Illumina HiSeq 2500	1
EGAD00001009155	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 5	HiSeq X Ten	1
EGAD00001009156	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 5	HiSeq X Ten	1
EGAD00001009157	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA535 passage 9	Illumina HiSeq 2500	1
EGAD00001009158	10x Genomics Single Cell Gene Expression for High grade serous ovarian carcinoma cell line TOV2295(R)	HiSeq X Ten	1
EGAD00001009159	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA604 passage 9	NextSeq 500	1
EGAD00001009160	10x Genomics Single Cell Gene Expression for Triple negative breast cancer patient-derived xenograft SA610 passage 3	HiSeq X Ten	1
EGAD00001009177	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA218	Illumina HiSeq 2500	1
EGAD00001009178	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA219	Illumina HiSeq 2500	1
EGAD00001009179	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA272	Illumina HiSeq 2500	1
EGAD00001009180	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA274	Illumina HiSeq 2500	1
EGAD00001009181	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA275	Illumina HiSeq 2500	1
EGAD00001009182	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA276	Illumina HiSeq 2500	1
EGAD00001009183	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA279	Illumina HiSeq 2500	1
EGAD00001009184	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA283	Illumina HiSeq 2500	1
EGAD00001009185	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA287	Illumina HiSeq 2500	1
EGAD00001009186	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA394	Illumina HiSeq 2500	1
EGAD00001009187	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA395	Illumina HiSeq 2500	1
EGAD00001009188	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA398	Illumina HiSeq 2500	1
EGAD00001009189	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA402	Illumina HiSeq 2500	1
EGAD00001009190	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA404	Illumina HiSeq 2500	1
EGAD00001009191	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA530	Illumina HiSeq 2000	1
EGAD00001009192	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA585	Illumina HiSeq 2500	1
EGAD00001009193	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA586	Illumina HiSeq 2500	1
EGAD00001009194	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA588	Illumina HiSeq 2500	1
EGAD00001009195	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA589	Illumina HiSeq 2500	1
EGAD00001009196	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA590	Illumina HiSeq 2500	1
EGAD00001009197	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA591	Illumina HiSeq 2500	1
EGAD00001009198	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA592	Illumina HiSeq 2500	1
EGAD00001009199	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA593	Illumina HiSeq 2500	1
EGAD00001009200	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA595	Illumina HiSeq 2500	1
EGAD00001009201	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA596	Illumina HiSeq 2500	1
EGAD00001009202	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA598	Illumina HiSeq 2500	1
EGAD00001009203	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA599	Illumina HiSeq 2500	1
EGAD00001009204	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA600	Illumina HiSeq 2500	1
EGAD00001009205	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA601	Illumina HiSeq 2500	1
EGAD00001009206	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA654	Illumina HiSeq 2500	1
EGAD00001009207	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA655	Illumina HiSeq 2500	1
EGAD00001009208	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA665	Illumina HiSeq 2500	1
EGAD00001009209	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA666	Illumina HiSeq 2500	1
EGAD00001009210	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA667	Illumina HiSeq 2500	1
EGAD00001009211	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA668	Illumina HiSeq 2500	1
EGAD00001009212	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA669	Illumina HiSeq 2500	1
EGAD00001009213	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA671	Illumina HiSeq 2500	1
EGAD00001009214	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA672	Illumina HiSeq 2500	1
EGAD00001009215	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA535	Illumina HiSeq 2000	1
EGAD00001009216	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1035	Illumina HiSeq X	1
EGAD00001009217	Whole genome sequencing of normal sample for triple negative breast cancer patient SA604	Illumina HiSeq 2500	1
EGAD00001009218	Whole genome sequencing of normal sample for triple negative breast cancer patient SA605	Illumina HiSeq 2500	1
EGAD00001009219	Whole genome sequencing of normal sample for triple negative breast cancer patient SA609	Illumina HiSeq 2500	1
EGAD00001009220	Whole genome sequencing of normal sample for triple negative breast cancer patient SA218	Illumina HiSeq 2500	1
EGAD00001009221	Whole genome sequencing of normal sample for triple negative breast cancer patient SA219	Illumina HiSeq 2500	1
EGAD00001009222	Whole genome sequencing of normal sample for triple negative breast cancer patient SA272	Illumina HiSeq 2500	1
EGAD00001009223	Whole genome sequencing of normal sample for triple negative breast cancer patient SA274	Illumina HiSeq 2500	1
EGAD00001009224	Whole genome sequencing of normal sample for triple negative breast cancer patient SA275	Illumina HiSeq 2500	1
EGAD00001009225	Whole genome sequencing of normal sample for triple negative breast cancer patient SA276	Illumina HiSeq 2500	1
EGAD00001009226	Whole genome sequencing of normal sample for triple negative breast cancer patient SA279	Illumina HiSeq 2500	1
EGAD00001009227	Whole genome sequencing of normal sample for triple negative breast cancer patient SA283	Illumina HiSeq 2500	1
EGAD00001009228	Whole genome sequencing of normal sample for triple negative breast cancer patient SA287	Illumina HiSeq 2500	1
EGAD00001009229	Whole genome sequencing of normal sample for triple negative breast cancer patient SA394	Illumina HiSeq 2500	1
EGAD00001009230	Whole genome sequencing of normal sample for triple negative breast cancer patient SA395	Illumina HiSeq 2500	1
EGAD00001009231	Whole genome sequencing of normal sample for triple negative breast cancer patient SA398	Illumina HiSeq 2500	1
EGAD00001009232	Whole genome sequencing of normal sample for triple negative breast cancer patient SA402	Illumina HiSeq 2500	1
EGAD00001009233	Whole genome sequencing of normal sample for triple negative breast cancer patient SA404	Illumina HiSeq 2500	1
EGAD00001009234	Whole genome sequencing of normal sample for triple negative breast cancer patient SA530	Illumina HiSeq 2500	1
EGAD00001009235	Whole genome sequencing of normal sample for triple negative breast cancer patient SA535	Illumina HiSeq 2000	1
EGAD00001009236	Whole genome sequencing of normal sample for triple negative breast cancer patient SA585	Illumina HiSeq 2500	1
EGAD00001009237	Whole genome sequencing of normal sample for triple negative breast cancer patient SA586	Illumina HiSeq 2500	1
EGAD00001009238	Whole genome sequencing of normal sample for triple negative breast cancer patient SA588	Illumina HiSeq 2500	1
EGAD00001009239	Whole genome sequencing of normal sample for triple negative breast cancer patient SA589	Illumina HiSeq 2500	1
EGAD00001009240	Whole genome sequencing of normal sample for triple negative breast cancer patient SA590	Illumina HiSeq 2500	1
EGAD00001009241	Whole genome sequencing of normal sample for triple negative breast cancer patient SA591	Illumina HiSeq 2500	1
EGAD00001009242	Whole genome sequencing of normal sample for triple negative breast cancer patient SA592	Illumina HiSeq 2500	1
EGAD00001009243	Whole genome sequencing of normal sample for triple negative breast cancer patient SA593	Illumina HiSeq 2500	1
EGAD00001009244	Whole genome sequencing of normal sample for triple negative breast cancer patient SA595	Illumina HiSeq 2500	1
EGAD00001009245	Whole genome sequencing of normal sample for triple negative breast cancer patient SA596	Illumina HiSeq 2500	1
EGAD00001009246	Whole genome sequencing of normal sample for triple negative breast cancer patient SA598	Illumina HiSeq 2500	1
EGAD00001009247	Whole genome sequencing of normal sample for triple negative breast cancer patient SA599	Illumina HiSeq 2500	1
EGAD00001009248	Whole genome sequencing of normal sample for triple negative breast cancer patient SA600	Illumina HiSeq 2500	1
EGAD00001009249	Whole genome sequencing of normal sample for triple negative breast cancer patient SA601	Illumina HiSeq 2500	1
EGAD00001009250	Whole genome sequencing of normal sample for triple negative breast cancer patient SA654	Illumina HiSeq 2500	1
EGAD00001009251	Whole genome sequencing of normal sample for triple negative breast cancer patient SA655	Illumina HiSeq 2500	1
EGAD00001009252	Whole genome sequencing of normal sample for triple negative breast cancer patient SA665	Illumina HiSeq 2500	1
EGAD00001009253	Whole genome sequencing of normal sample for triple negative breast cancer patient SA667	Illumina HiSeq 2500	1
EGAD00001009254	Whole genome sequencing of normal sample for triple negative breast cancer patient SA668	Illumina HiSeq 2500	1
EGAD00001009255	Whole genome sequencing of normal sample for triple negative breast cancer patient SA669	Illumina HiSeq 2500	1
EGAD00001009256	Whole genome sequencing of normal sample for triple negative breast cancer patient SA671	Illumina HiSeq 2500	1
EGAD00001009257	Whole genome sequencing of normal sample for triple negative breast cancer patient SA672	Illumina HiSeq 2500	1
EGAD00001009258	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1035	Illumina HiSeq X	1
EGAD00001009259	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA994	Illumina HiSeq X	1
EGAD00001009260	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA604	Illumina HiSeq 2500	1
EGAD00001009261	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA605	Illumina HiSeq 2500	1
EGAD00001009262	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA609	Illumina HiSeq 2500	1
EGAD00001009316	Single Cell Genome Sequence for Triple negative breast cancer patient-derived xenograft SA609 passage 3 on DLP+ library A95618B	NextSeq 550	15
EGAD00001009319	Single Cell Genome Sequence for triple negative breast cancer patient SA1162SB on DLP+ library A95628A	HiSeq X Ten	3
EGAD00001009320	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1051D passage 1 on DLP+ library A95629B	HiSeq X Ten	3
EGAD00001009321	Single Cell Genome Sequence for immortalized breast epithelium - BRCA1-/- Tp53-/- cell line 184-hTERT-22 L9 83.86 on DLP+ library A95632A	Illumina HiSeq 2500	7
EGAD00001009322	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA609 passage 6 on DLP+ library A95632C	NextSeq 550	8
EGAD00001009323	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1091A passage 1 on DLP+ library A95634A	HiSeq X Ten	3
EGAD00001009324	Single Cell Genome Sequence for immortalized breast epithelium - BRCA2-/-; Tp53-/- cell line 184-hTERT-22 L9 116.126 on DLP+ library A95635A	Illumina HiSeq 2500	4
EGAD00001009325	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1052J passage 1 on DLP+ library A95650A	HiSeq X Ten	3
EGAD00001009326	Single Cell Genome Sequence for immortalized breast epithelium BRCA2+/- Tp53-/- cell line 184-hTert L9 116.66 on DLP+ library A95652A	HiSeq X Ten	2
EGAD00001009327	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1049A passage 1 on DLP+ library A95652B	HiSeq X Ten	3
EGAD00001009340	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA673	Illumina HiSeq 2500	1
EGAD00001009341	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA674	Illumina HiSeq 2500	1
EGAD00001009342	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA675	Illumina HiSeq 2500	1
EGAD00001009343	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA676	Illumina HiSeq 2500	1
EGAD00001009344	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA677	Illumina HiSeq 2500	1
EGAD00001009345	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA678	Illumina HiSeq 2500	1
EGAD00001009346	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA679	Illumina HiSeq 2500	1
EGAD00001009347	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA680	Illumina HiSeq 2500	1
EGAD00001009348	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA681	Illumina HiSeq 2500	1
EGAD00001009349	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA682	Illumina HiSeq 2500	1
EGAD00001009350	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA683	Illumina HiSeq 2500	1
EGAD00001009351	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA221	Illumina HiSeq 2000	1
EGAD00001009352	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA238	Illumina HiSeq 2000	1
EGAD00001009353	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA239	Illumina HiSeq 2000	1
EGAD00001009354	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA300	Illumina HiSeq 2000	1
EGAD00001009355	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA423	Illumina HiSeq 2000	1
EGAD00001009356	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA425	Illumina HiSeq 2000	1
EGAD00001009357	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA495	Illumina HiSeq 2000	1
EGAD00001009358	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA286	Illumina HiSeq 2000	1
EGAD00001009359	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA289	Illumina HiSeq 2000	1
EGAD00001009360	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA291	Illumina HiSeq 2000	1
EGAD00001009361	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA280	Illumina HiSeq 2000	1
EGAD00001009362	Whole genome sequencing of normal sample for triple negative breast cancer patient SA221	Illumina HiSeq 2000	1
EGAD00001009363	Whole genome sequencing of normal sample for triple negative breast cancer patient SA238	Illumina HiSeq 2000	1
EGAD00001009364	Whole genome sequencing of normal sample for triple negative breast cancer patient SA239	Illumina HiSeq 2000	1
EGAD00001009365	Whole genome sequencing of normal sample for triple negative breast cancer patient SA280	Illumina HiSeq 2000	1
EGAD00001009366	Whole genome sequencing of normal sample for triple negative breast cancer patient SA286	Illumina HiSeq 2000	1
EGAD00001009367	Whole genome sequencing of normal sample for triple negative breast cancer patient SA289	Illumina HiSeq 2000	1
EGAD00001009368	Whole genome sequencing of normal sample for triple negative breast cancer patient SA291	Illumina HiSeq 2000	1
EGAD00001009369	Whole genome sequencing of normal sample for triple negative breast cancer patient SA300	Illumina HiSeq 2000	1
EGAD00001009370	Whole genome sequencing of normal sample for triple negative breast cancer patient SA423	Illumina HiSeq 2000	1
EGAD00001009371	Whole genome sequencing of normal sample for triple negative breast cancer patient SA425	Illumina HiSeq 2000	1
EGAD00001009372	Whole genome sequencing of normal sample for triple negative breast cancer patient SA495	Illumina HiSeq 2000	1
EGAD00001009373	Whole genome sequencing of normal sample for triple negative breast cancer patient SA673	Illumina HiSeq 2500	1
EGAD00001009374	Whole genome sequencing of normal sample for triple negative breast cancer patient SA674	Illumina HiSeq 2500	1
EGAD00001009375	Whole genome sequencing of normal sample for triple negative breast cancer patient SA675	Illumina HiSeq 2500	1
EGAD00001009376	Whole genome sequencing of normal sample for triple negative breast cancer patient SA676	Illumina HiSeq 2500	1
EGAD00001009377	Whole genome sequencing of normal sample for triple negative breast cancer patient SA677	Illumina HiSeq 2500	1
EGAD00001009378	Whole genome sequencing of normal sample for triple negative breast cancer patient SA678	Illumina HiSeq 2500	1
EGAD00001009379	Whole genome sequencing of normal sample for triple negative breast cancer patient SA679	Illumina HiSeq 2500	1
EGAD00001009380	Whole genome sequencing of normal sample for triple negative breast cancer patient SA680	Illumina HiSeq 2500	1
EGAD00001009381	Whole genome sequencing of normal sample for triple negative breast cancer patient SA681	Illumina HiSeq 2500	1
EGAD00001009382	Whole genome sequencing of normal sample for triple negative breast cancer patient SA682	Illumina HiSeq 2500	1
EGAD00001009383	Whole genome sequencing of normal sample for triple negative breast cancer patient SA683	Illumina HiSeq 2500	1
EGAD00001009428	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1181A passage 1 on DLP library A108765A	HiSeq X Ten	3
EGAD00001009429	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1182E passage 1 on DLP+ library A108847B	HiSeq X Ten	4
EGAD00001009430	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA610 passage 3 on DLP+ library A110660A	HiSeq X Ten	4
EGAD00001009431	Single Cell Genome Sequence for Immortalized breast epithelium BRCA2+/- Tp53-/- cell line 184-hTert L9 116.66 cell line SA1188 on DLP+ library A118357B	HiSeq X Ten	3
EGAD00001009432	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA605 passage 3 on DLP+ library A118368B	HiSeq X Ten	4
EGAD00001009433	Single Cell Genome Sequence for Telomerase immortalized breast epithelium cell line 184-hTERT 85.14 p20 cell line AT135 on DLP+ library A118389B	NextSeq 2000	4
EGAD00001009434	Single Cell Genome Sequence for Immortalized breast epithelium BRCA2+/- Tp53-/- cell line 184-hTert L9 116.66 cell line SA1188 on DLP+ library A118425B	HiSeq X Ten	3
EGAD00001009435	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1050B passage 1, patient-derived xenograft SA1050E passage 1 on DLP+ library A118782A	HiSeq X Ten	6
EGAD00001009436	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1050B passage 1, patient-derived xenograft SA1050E passage 1 on DLP+ library A118784A	HiSeq X Ten	6
EGAD00001009437	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA610 passage 3, patient-derived xenograft SA1096C passage 1 on DLP+ library A118790A	HiSeq X Ten	6
EGAD00001009438	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1184D passage 1 on DLP+ library A118797B	HiSeq X Ten	4
EGAD00001009439	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1162B passage 1, patient-derived xenograft SA1096B passage 1 on DLP+ library A118804A	HiSeq X Ten	6
EGAD00001009440	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1096B passage 1 on DLP+ library A118808A	HiSeq X Ten	4
EGAD00001009441	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1096C passage 1 on DLP+ library A118808B	HiSeq X Ten	4
EGAD00001009442	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1180C passage 1 on DLP+ library A118812B	HiSeq X Ten	4
EGAD00001009443	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1162B passage 1 on DLP+ library A118814B	HiSeq X Ten	4
EGAD00001009444	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1180C passage 1 on DLP+ library A118816A	HiSeq X Ten	4
EGAD00001009445	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1184D passage 1 on DLP+ library A118857B	HiSeq X Ten	4
EGAD00001009446	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1053F passage 1 on DLP+ library A95663A	HiSeq X Ten	3
EGAD00001009447	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient SA1162SA on DLP+ library A95668A	HiSeq X Ten	3
EGAD00001009448	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 5 on DLP+ library A95670A	NextSeq 550	3
EGAD00001009449	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 6 on DLP+ library A95670B	NextSeq 550	3
EGAD00001009450	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1096A passage 1 on DLP+ library A95717A	HiSeq X Ten	3
EGAD00001009451	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 6 on DLP+ library A95722A	HiSeq X Ten	7
EGAD00001009452	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 2 on DLP+ library A96109A	HiSeq X Ten	5
EGAD00001009453	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1049A passage on DLP+ library A96113A	NextSeq 550	6
EGAD00001009454	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA609 passage 8 on DLP+ library A96130A	HiSeq X Ten	3
EGAD00001009455	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient SA1162SA on DLP+ library A96142B	HiSeq X Ten	3
EGAD00001009456	Single Cell Genome Sequence for triple negative breast cancer patient SA1135, patient SA1162SA on DLP+ library A96154A	HiSeq X Ten	5
EGAD00001009457	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 8 on DLP+ library A96161A	HiSeq X Ten	5
EGAD00001009458	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 2, patient-derived xenograft SA611 passage 3 on DLP+ library A96171A	HiSeq X Ten	7
EGAD00001009459	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 15 on DLP+ library A96173A	HiSeq X Ten	7
EGAD00001009460	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 11 on DLP+ library A96174A	HiSeq X Ten	3
EGAD00001009461	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 7 on DLP+ library A96175A	HiSeq X Ten	3
EGAD00001009462	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 6 on DLP+ library A96177C	HiSeq X Ten	3
EGAD00001009463	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 6 on DLP+ library A96180A	HiSeq X Ten	3
EGAD00001009464	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 11, patient-derived xenograft SA609 passage 7 on DLP+ library A96187A	HiSeq X Ten	10
EGAD00001009465	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1049C passage 1 on DLP+ library A96189A	HiSeq X Ten	3
EGAD00001009466	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1051A passage 1 on DLP+ library A96190B	HiSeq X Ten	3
EGAD00001009467	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1093C passage 1, patient SA1147 on DLP+ library A96192A	HiSeq X Ten	5
EGAD00001009468	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1053B passage 1 on DLP+ library A96194A	HiSeq X Ten	3
EGAD00001009469	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1053E passage 1 on DLP+ library A96194B	HiSeq X Ten	3
EGAD00001009470	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1052D passage 1 on DLP+ library A96200B	HiSeq X Ten	3
EGAD00001009471	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1049A passage 1 on DLP+ library A96205B	HiSeq X Ten	-
EGAD00001009472	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1050F passage 1 on DLP+ library A96206B	HiSeq X Ten	3
EGAD00001009473	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1051A passage 1 on DLP+ library A96207A	HiSeq X Ten	3
EGAD00001009474	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1052B passage 1 on DLP+ library A96207B	HiSeq X Ten	3
EGAD00001009475	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient SA1047B on DLP+ library A96210B	HiSeq X Ten	3
EGAD00001009476	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 7 on DLP+ library A96212B	HiSeq X Ten	5
EGAD00001009477	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 6, cell line SA1090 on DLP+ library A96213A	HiSeq X Ten	5
EGAD00001009478	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient SA1105, patient SA1103, patient SA1106, patient SA1104 on DLP+ library A96222A	NextSeq 550	11
EGAD00001009479	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA919 passage 7, patient-derived xenograft SA1050A passage 1 on DLP+ library A98181A	HiSeq X Ten	6
EGAD00001009480	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA530 passage 3 on DLP+ library A98240A	HiSeq X Ten	4
EGAD00001009481	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient SA1096A, patient-derived xenograft SA1052D passage 1 on DLP+ library A98243B	HiSeq X Ten	6
EGAD00001009486	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1050A passage 1, patient SA1234 on DLP+ library A98279A	HiSeq X Ten	-
EGAD00001009487	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA501 passage 2 on DLP+ library A95621B	Illumina HiSeq 2500	1
EGAD00001009488	Single Cell Genome Sequence for Immortalized breast epithelium - BRCA2-/-; Tp53-/- cell line 184-hTERT-22 L9 112.109 cell line SA1055 on DLP+ library A95621A	Illumina HiSeq 2500	3
EGAD00001009489	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient-derived xenograft SA1050D passage 1 on DLP+ library A95717B	HiSeq X Ten	3
EGAD00001009513	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 8 on DLP+ library A96141A	HiSeq X Ten	212
EGAD00001009517	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA533	Illumina HiSeq 2000	1
EGAD00001009518	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA409	Illumina HiSeq 2500	1
EGAD00001009519	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA420	Illumina HiSeq 2000	1
EGAD00001009520	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA296	Illumina HiSeq 2500	1
EGAD00001009521	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA597	Illumina HiSeq 2500	1
EGAD00001009522	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA232	Illumina HiSeq 2000	1
EGAD00001009523	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA211	Illumina HiSeq X	1
EGAD00001009524	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA230	Illumina HiSeq X	1
EGAD00001009525	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA234	Illumina HiSeq X	1
EGAD00001009526	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA278	Illumina HiSeq X	1
EGAD00001009527	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA101	Illumina HiSeq X	1
EGAD00001009528	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA212	Illumina HiSeq X	1
EGAD00001009529	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA214	Illumina HiSeq X	1
EGAD00001009530	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA224	Illumina HiSeq X	1
EGAD00001009531	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA225	Illumina HiSeq X	1
EGAD00001009532	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA226	Illumina HiSeq X	1
EGAD00001009533	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA228	Illumina HiSeq X	1
EGAD00001009534	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA229	Illumina HiSeq X	1
EGAD00001009535	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA231	Illumina HiSeq X	1
EGAD00001009536	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA233	Illumina HiSeq X	1
EGAD00001009537	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA237	Illumina HiSeq X	1
EGAD00001009538	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA271	Illumina HiSeq X	1
EGAD00001009539	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA277	Illumina HiSeq X	1
EGAD00001009540	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA284	Illumina HiSeq X	1
EGAD00001009541	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA399	Illumina HiSeq X	1
EGAD00001009542	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA294	Illumina HiSeq X	1
EGAD00001009543	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA285	Illumina HiSeq 2000	1
EGAD00001009544	Whole genome sequencing of normal sample for triple negative breast cancer patient SA101	Illumina HiSeq X	1
EGAD00001009545	Whole genome sequencing of normal sample for triple negative breast cancer patient SA211	Illumina HiSeq X	1
EGAD00001009546	Whole genome sequencing of normal sample for triple negative breast cancer patient SA212	Illumina HiSeq X	1
EGAD00001009547	Whole genome sequencing of normal sample for triple negative breast cancer patient SA214	Illumina HiSeq X	1
EGAD00001009548	Whole genome sequencing of normal sample for triple negative breast cancer patient SA224	Illumina HiSeq X	1
EGAD00001009549	Whole genome sequencing of normal sample for triple negative breast cancer patient SA225	Illumina HiSeq X	1
EGAD00001009550	Whole genome sequencing of normal sample for triple negative breast cancer patient SA226	Illumina HiSeq X	1
EGAD00001009551	Whole genome sequencing of normal sample for triple negative breast cancer patient SA228	Illumina HiSeq X	1
EGAD00001009552	Whole genome sequencing of normal sample for triple negative breast cancer patient SA229	Illumina HiSeq X	1
EGAD00001009553	Whole genome sequencing of normal sample for triple negative breast cancer patient SA230	Illumina HiSeq X	1
EGAD00001009554	Whole genome sequencing of normal sample for triple negative breast cancer patient SA231	Illumina HiSeq X	1
EGAD00001009555	Whole genome sequencing of normal sample for triple negative breast cancer patient SA232	Illumina HiSeq 2000	1
EGAD00001009556	Whole genome sequencing of normal sample for triple negative breast cancer patient SA233	Illumina HiSeq X	1
EGAD00001009557	Whole genome sequencing of normal sample for triple negative breast cancer patient SA234	Illumina HiSeq X	1
EGAD00001009558	Whole genome sequencing of normal sample for triple negative breast cancer patient SA237	Illumina HiSeq X	1
EGAD00001009559	Whole genome sequencing of normal sample for triple negative breast cancer patient SA271	Illumina HiSeq X	1
EGAD00001009560	Whole genome sequencing of normal sample for triple negative breast cancer patient SA277	Illumina HiSeq X	1
EGAD00001009561	Whole genome sequencing of normal sample for triple negative breast cancer patient SA278	Illumina HiSeq X	1
EGAD00001009562	Whole genome sequencing of normal sample for triple negative breast cancer patient SA284	Illumina HiSeq X	1
EGAD00001009563	Whole genome sequencing of normal sample for triple negative breast cancer patient SA285	Illumina HiSeq 2500	1
EGAD00001009564	Whole genome sequencing of normal sample for triple negative breast cancer patient SA290	Illumina HiSeq 2500	1
EGAD00001009565	Whole genome sequencing of normal sample for triple negative breast cancer patient SA294	Illumina HiSeq X	1
EGAD00001009566	Whole genome sequencing of normal sample for triple negative breast cancer patient SA296	Illumina HiSeq 2500	1
EGAD00001009567	Whole genome sequencing of normal sample for triple negative breast cancer patient SA399	Illumina HiSeq X	1
EGAD00001009568	Whole genome sequencing of normal sample for triple negative breast cancer patient SA400	Illumina HiSeq X	1
EGAD00001009569	Whole genome sequencing of normal sample for triple negative breast cancer patient SA409	Illumina HiSeq 2500	1
EGAD00001009570	Whole genome sequencing of normal sample for triple negative breast cancer patient SA420	Illumina HiSeq 2500	1
EGAD00001009571	Whole genome sequencing of normal sample for triple negative breast cancer patient SA533	Illumina HiSeq 2000	1
EGAD00001009572	Whole genome sequencing of normal sample for triple negative breast cancer patient SA597	Illumina HiSeq 2500	1
EGAD00001009573	Whole genome sequencing of normal sample for triple negative breast cancer patient SA997	Illumina HiSeq X	1
EGAD00001009574	Whole genome sequencing of normal sample for triple negative breast cancer patient SA998	Illumina HiSeq X	1
EGAD00001009575	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA416	Illumina HiSeq X	1
EGAD00001009576	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA400	Illumina HiSeq X	1
EGAD00001009577	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA290	Illumina HiSeq 2000	1
EGAD00001009578	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA288	Illumina HiSeq 2500	1
EGAD00001009579	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA299	Illumina HiSeq 2000	1
EGAD00001009580	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA095	Illumina HiSeq 2000	1
EGAD00001009581	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA415	Illumina HiSeq X	1
EGAD00001009582	Whole genome sequencing of normal sample for triple negative breast cancer patient SA718	Illumina HiSeq 2500	1
EGAD00001009583	Whole genome sequencing of normal sample for triple negative breast cancer patient SA720	Illumina HiSeq 2500	1
EGAD00001009584	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA718	Illumina HiSeq 2500	1
EGAD00001009585	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA720	Illumina HiSeq 2500	1
EGAD00001009586	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1017	Illumina HiSeq X	1
EGAD00001009587	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1026	Illumina HiSeq X	1
EGAD00001009588	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1027	Illumina HiSeq X	1
EGAD00001009589	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1028	Illumina HiSeq X	1
EGAD00001009590	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1040	Illumina HiSeq X	1
EGAD00001009591	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1064	Illumina HiSeq X	1
EGAD00001009592	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1065	Illumina HiSeq X	1
EGAD00001009593	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1069	Illumina HiSeq X	1
EGAD00001009594	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1073	Illumina HiSeq X	1
EGAD00001009595	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1074	Illumina HiSeq X	1
EGAD00001009596	Whole genome sequencing of normal sample for triple negative breast cancer patient SA576	Illumina HiSeq 2000	1
EGAD00001009597	Whole genome sequencing of normal sample for triple negative breast cancer patient SA610	Illumina HiSeq 2500	1
EGAD00001009598	Whole genome sequencing of normal sample for triple negative breast cancer patient SA992	Illumina HiSeq X	1
EGAD00001009599	Whole genome sequencing of normal sample for triple negative breast cancer patient SA994	Illumina HiSeq X	1
EGAD00001009600	Whole genome sequencing of normal sample for triple negative breast cancer patient SA095	Illumina HiSeq 2000	1
EGAD00001009601	Whole genome sequencing of normal sample for triple negative breast cancer patient SA288	Illumina HiSeq 2500	1
EGAD00001009602	Whole genome sequencing of normal sample for triple negative breast cancer patient SA299	Illumina HiSeq 2000	1
EGAD00001009603	Whole genome sequencing of normal sample for triple negative breast cancer patient SA415	Illumina HiSeq X	1
EGAD00001009604	Whole genome sequencing of normal sample for triple negative breast cancer patient SA666	Illumina HiSeq 2500	1
EGAD00001009605	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1065	Illumina HiSeq X	1
EGAD00001009606	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1064	Illumina HiSeq X	1
EGAD00001009607	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1026	Illumina HiSeq X	1
EGAD00001009608	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1069	Illumina HiSeq X	1
EGAD00001009609	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1017	Illumina HiSeq X	1
EGAD00001009610	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1027	Illumina HiSeq X	1
EGAD00001009611	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1073	Illumina HiSeq X	1
EGAD00001009612	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1074	Illumina HiSeq X	1
EGAD00001009613	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA576	Illumina HiSeq 2500	1
EGAD00001009614	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1028	Illumina HiSeq X	1
EGAD00001009615	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1040	Illumina HiSeq X	1
EGAD00001009616	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA992	Illumina HiSeq X	1
EGAD00001009617	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA610	Illumina HiSeq 2500	1
EGAD00001009618	Whole genome sequencing of normal sample for triple negative breast cancer patient SA416	Illumina HiSeq X	1
EGAD00001009619	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1070	Illumina HiSeq X	1
EGAD00001009620	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1070	Illumina HiSeq X	1
EGAD00001009621	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA997	Illumina HiSeq X	1
EGAD00001009644	Single Cell Genome Sequence for high grade serous ovarian carcinoma patient SA1105, patient SA1106 on DLP+ library A96168B	HiSeq X Ten	5
EGAD00001009645	Single Cell Genome Sequence for Immortalized lymphoblastoid cell line GM18507 cell line SA928,Triple negative breast cancer patient-derived xenograft SA609 passage 2 patient-derived xenograft SA609 passage 2 on DLP+ library A96228A	HiSeq X Ten	6
EGAD00001009646	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA530 passage 3 on DLP+ library A98247A	HiSeq X Ten	-
EGAD00001009672	Whole genome sequencing of normal sample for triple negative breast cancer patient SA1058	Illumina HiSeq X	1
EGAD00001009673	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA1058	Illumina HiSeq X	1
EGAD00001009674	Whole genome sequencing of tumour sample for triple negative breast cancer patient SA998	Illumina HiSeq X	1
EGAD00001009777	Single Cell Genome Sequence for triple negative breast cancer patient-derived xenograft SA604 passage 8 on DLP+ library A96141A	HiSeq X Ten	1

Publications	Citations
Single-cell genomic variation induced by mutational processes in cancer. Funnell T, O'Flanagan CH, Williams MJ, McPherson A, McKinney S, Kabeer F, Lee H, Salehi S, Vázquez-García I, Shi H, Leventhal E, Masud T, Eirew P, Yap D, Zhang AW, Lim JLP, Wang B, Brimhall J, Biele J, Ting J, Au V, Van Vliet M, Liu YF, Beatty S, Lai D, Pham J, Grewal D, Abrams D, Havasov E, Leung S, Bojilova V, Moore RA, Rusk N, Uhlitz F, Ceglia N, Weiner AC, Zaikova E, Douglas JM, Zamarin D, Weigelt B, Kim SH, Da Cruz Paula A, Reis-Filho JS, Martin SD, Li Y, Xu H, de Algara TR, Lee SR, Llanos VC, Huntsman DG, McAlpine JN, IMAXT Consortium, Shah SP, Aparicio S. Nature 612: 2022 106-115	25
Allele-specific transcriptional effects of subclonal copy number alterations enable genotype-phenotype mapping in cancer cells. Shi H, Williams MJ, Satas G, Weiner AC, McPherson A, Shah SP. Nat Commun 15: 2024 2482	0

Publications

Citations

Single-cell genomic variation induced by mutational processes in cancer.
Funnell T, O'Flanagan CH, Williams MJ, McPherson A, McKinney S, Kabeer F, Lee H, Salehi S, Vázquez-García I, Shi H, Leventhal E, Masud T, Eirew P, Yap D, Zhang AW, Lim JLP, Wang B, Brimhall J, Biele J, Ting J, Au V, Van Vliet M, Liu YF, Beatty S, Lai D, Pham J, Grewal D, Abrams D, Havasov E, Leung S, Bojilova V, Moore RA, Rusk N, Uhlitz F, Ceglia N, Weiner AC, Zaikova E, Douglas JM, Zamarin D, Weigelt B, Kim SH, Da Cruz Paula A, Reis-Filho JS, Martin SD, Li Y, Xu H, de Algara TR, Lee SR, Llanos VC, Huntsman DG, McAlpine JN, IMAXT Consortium, Shah SP, Aparicio S. Nature 612: 2022 106-115

Allele-specific transcriptional effects of subclonal copy number alterations enable genotype-phenotype mapping in cancer cells.
Shi H, Williams MJ, Satas G, Weiner AC, McPherson A, Shah SP. Nat Commun 15: 2024 2482