Study
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001006364 | Cancer Genomics |
Study Description
Study Datasets 1 dataset.
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| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001008985 |
We profiled CD34+ enriched cells from GCSF mobilized bone marrow samples (n = 4) using single-cell RNA sequencing (10X) with targeted genotyping, and single-cell DNA methylation (RRBS) with single-cell RNA sequencing (Smart-Seq2) and targeted genotyping.
A 5th CH bone marrow aspirate sample was obtained to validate observed results.
|
Illumina NovaSeq 6000 | 5 |
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