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Plasma whole genome sequencing from patients with stage IV colorectal cancer and microsatellite instability

This study aims to explore genomic features of cancer in plasma WGS data from patients with advanced colorectal cancer. Cell-free DNA (cfDNA) was extracted from plasma using the QIAamp Circulating Nucleic Acid Kit. Libraries were prepared with 5 to 250 ng of cfDNA using the NEBNext DNA Library Prep Kit.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001008999 Illumina HiSeq 2000 37
Publications Citations
Genome-wide mutational signatures in low-coverage whole genome sequencing of cell-free DNA.
Nat Commun 13: 2022 4953