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CNV profile in HSP90 inhibitor resistant K562 cells

Analysis of the acquired copy number profile in K562 cell which got resistant against HSP90 inhibitors.

1 Dataset 1 Publication

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Dataset ID	Description	Technology	Samples
EGAD00010002336	K562 cells were treated with different HSP90 inhibitors (PuH71 and Coumermycin A1) and the CNV profil was compared to the parental K562 (untreated). In addition, the CNV profile of HSP90AB1 knockout K562 cells was analyzed.	Illumina NextSeq 550	4

Publications	Citations
Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells. Vogt M, Dienstbier N, Schliehe-Diecks J, Scharov K, Tu JW, Gebing P, Hogenkamp J, Bilen BS, Furlan S, Picard D, Remke M, Yasin L, Bickel D, Kalia M, Iacoangeli A, Lenz T, Stühler K, Pandyra AA, Hauer J, Fischer U, Wagener R, Borkhardt A, Bhatia S. Cell Death Dis 14: 2023 799	12