Blina Tumour project

Study ID Alternative Stable ID Type
EGAS00001006486 Whole Genome Sequencing

Study Description

The aim of this study is to reconstruct the embryology of childhood tumours.

Study Datasets 1 dataset.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
Children with ALL treated with anti-CD19 therapy occasionally develop a phenotypically distinct AML. However, the precise clonal origin of such class switch leukemias remains unresolved. Here, we reconstructed the evolution of leukemia in a child with primary ALL, two ALL relapses and AML after treatment with anti-CD19 CAR-T and blinatumomab through whole-genome sequencing. The phylogeny revealed that the AML was a monoclonal outgrowth descending from the initial ALL and harbored biallelic loss ... (Show More)
Illumina NovaSeq 6000 8

Who archives the data?

There are no publications available