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HLF COPD Transcriptomics

We generated transcriptomes of primary human lung fibroblasts (HLFs) isolated from distal parenchyma of ex-smoker controls and COPD patients, with both mild and severe disease. RNA sequencing analysis demonstrated dysregulation of genes involved in proliferation, DNA repair, and extracellular matrix organization.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001009405 NextSeq 500 11
Publications Citations
High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD.
EMBO J 42: 2023 e111272