Whole blood transcriptomic analysis of ANCA-associated vasculitis

Study ID Alternative Stable ID Type
EGAS00001006704 Other

Study Description

Whole blood mRNA sequencing from 30 patients with AAV (granulomatosis with polyangiitis/GPA, n=22) and microscopic polyangiitis (MPA, n=8) combined with functional enrichment and network analysis for aberrant pathways. Key genes and pathways were validated in an independent cohort of 18 AAV patients. Co-expression network and hierarchical clustering analysis, identified molecular endotypes. Multi-level transcriptional overlap analysis to SLE was based on our published data from 142 patients.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
This dataset contains RNA-sequencing of whole blood samples from Healthy Controls (n=11), AAV patients (n=30, GPAn=22, MPAn=8).
NextSeq 500 6

Who archives the data?

There are no publications available