Study
A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001006716 | Other |
Study Description
We identified a gradated transcriptional program of coordinately regulated inflammation-suppressive genes in psoriatic resident memory T cells. This dataset includes bulk RNA-seq for CRISPR-based deactivation of two core components of this inflammation-suppressive program, ZFP36L2 and ZFP36, in human PBMCs. It also includes scRNA-seq of cutaneous immune cells from psoriasis patients before and during therapeutic IL-23 blockade.
Study Datasets 1 dataset.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001009677 |
There are two datasets:
1. scRNA-seq of human cutaneous immune cells from psoriasis patients. These include pre- and post-Tildrakizumab treated patients and come in a BAM file format.
19006FL-25-01
19006FL-38-01
19006FL-32-01-03
19006FL-33-01
19006FL-28-01-05
19006FL-35-01-01
2. RNA-seq of ZFP36L2 CRISPIR deleted Human T cells are FASTQ ... (Show More)
|
Illumina HiSeq 4000,Illumina NovaSeq 6000 | 17 |
Who archives the data?
