Analyzing the expression profiles of genes in ureters with and without indwelling stents using RNAseq 

Study ID Alternative Stable ID Type
EGAS00001006855 Other

Study Description

The objective of the work is to explore the pathways and mechanisms driving inflammation and fibrosis in stented ureters. In total, 6 pigs underwent cystoscopic unilateral ureteral stent insertion for 14 days. Ureteral tissue was harvested in 3 pigs, while the remaining 3 pigs had their stents removed, and were recovered for 7 days. Three separate pigs served as controls. Stents cause significant inflammation and fibrosis of ureters. Gene set enrichment analysis confirmed fibrotic changes and tissue proliferation and suggests that epithelial-mesenchymal transition is a driver of fibrosis.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
This dataset includes 2*76bp RNA-seq reads from 9 pigs sequenced using Illumina NextSeq500.
NextSeq 500 9

Who archives the data?

There are no publications available