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PELICAN45 RNAseq Dataset

To better understand the biology of prostate cancer, we performed RNAseq in cancerous (primary and metastatic) and noncancerous tissues in the PELICAN45 cohort. The PELICAN45 RNAseq samples include androgen-deprived metastasis samples from the PELICAN33 consenting rapid autopsy study participants, whose identifiers are A1, A2, etc. The PELICAN45 RNAseq dataset also includes data from non-androgen deprived metastases in an additional 12 men. These samples are identified as PB50, PB133, etc.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001009997 HiSeq X Ten 130
Publications Citations
The evolutionary history of lethal metastatic prostate cancer.
Nature 520: 2015 353-357
Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.
Cold Spring Harb Mol Case Stud 2: 2016 a000752
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
Nat Genet 50: 2018 682-692
Expression of neuroendocrine differentiation markers in lethal metastatic castration-resistant prostate cancer.
Pathol Res Pract 214: 2018 848-856
Pan-cancer analysis of whole genomes.
Nature 578: 2020 82-93
Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy.
Nat Commun 11: 2020 5070
Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine.
Eur Urol Open Sci 30: 2021 47-62
Identification of long noncoding RNAs with aberrant expression in prostate cancer metastases.
Endocr Relat Cancer 30: 2023 e220247