Study

Multiomic Sequencing of Paired Primary and Metastatic Small Bowel Carcinoids

Study ID Alternative Stable ID Type
EGAS00001006988 Other

Study Description

Small bowel carcinoids are insidious tumors that often have metastatic spread at the time of diagnosis. Limited studies on the mutational landscape of carcinoids indicate that the tumors have a relatively low mutational burden. Loss of chromosome 18q and loss of CDKN1B have been reported in a minority of tumors. The development of targeted therapies will depend upon the identification of mutations that drive the pathogenesis and metastasis of carcinoid tumors.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
EGAD00001010036
This dataset includes trios of germline/constitutional, primary tumor (small bowel carcinoid), and metastatic tumor (liver) trios for 5 patients (i.e. 15 samples total). Constitutional, primary tumor, and metastatic tumor samples all underwent whole exome sequencing (WES or WXS). Primary and metastatic tumor samples underwent RNA sequencing (RNA-seq).
15

Who archives the data?

There are no publications available