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Relevance of TMPRSS2, CD163/CD206 and CD33 in clinical severity stratification of COVID-19

Our main objective is to incorporate new markers to classify COVID-19 patients based on mild or severe disease progression. To achieve this, we characterize SNP genotypes in critical genes involved in SARS-CoV infection (ACE2 (rs2285666), MX1 (rs469390), and TMPRSS2 (rs2070788) variants) and study the monocyte population by mass cytometry (CyTOF). Finally, the results obtained will be integrated to search for the best set of predictors of disease aggressiveness.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00010002445 7900HT Fast Real-Time PCR System 66
Publications Citations
Relevance of <i>TMPRSS2</i>, CD163/CD206, and CD33 in clinical severity stratification of COVID-19.
Front Immunol 13: 2022 1094644