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AT2 COPD Methylomics

We generated genome-wide DNA methylation maps at single CpG resolution of primary human lung AT2 cells isolated from distal parenchyma of ex-smoker controls and COPD patients, with both mild and severe disease

Type: Other
Archiver: European Genome-phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001011116	WGBS of FACS sorted AT2 cells from ex-smokers with (n=6) and without (n=3) COPD at different disease stages. Fastq files are provided.	Illumina HiSeq 2500	11

Publications	Citations
Epigenetic dysregulation of IRF9 drives excessive interferon signaling in COPD. Llamazares-Prada M, Schwartz U, Pease DF, Pohl ST, Ackesson D, Li R, Behrendt A, Tamas R, Stammler V, Richter M, Muley T, Scherer M, Hey J, Espinet E, Heußel CP, Warth A, Schneider MA, Winter H, Herth FJ, Imbusch CD, Brors B, Benes V, Wyatt D, Jurkowski TP, Stahl HF, Plass C, Jurkowska RZ. EMBO Mol Med 18: 2026 1202-1234	0

Publications

Citations

Epigenetic dysregulation of IRF9 drives excessive interferon signaling in COPD.
Llamazares-Prada M, Schwartz U, Pease DF, Pohl ST, Ackesson D, Li R, Behrendt A, Tamas R, Stammler V, Richter M, Muley T, Scherer M, Hey J, Espinet E, Heußel CP, Warth A, Schneider MA, Winter H, Herth FJ, Imbusch CD, Brors B, Benes V, Wyatt D, Jurkowski TP, Stahl HF, Plass C, Jurkowska RZ. EMBO Mol Med 18: 2026 1202-1234