Sequencing of patient tissue and patient derived organoids in colon cancer

Multiome (ATAC + RNA) sequencing of cancerous primary tissue and cancer organoids derived from the same patient. Nanopore and whole exome sequencing of selected samples.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001015504	Multiome sequencing of patient tissue and patient derived organoids in colon cancer	Illumina NovaSeq 6000	22
EGAD00001015548	HCA Organoids \| Colon - Cancer, Whole Exome Sequencing (WES)	Illumina NovaSeq 6000	23

Publications	Citations
Single-cell multi-omics characterize colorectal tumors, adjacent healthy tissue and matched (tumor) organoids identifying CRC-unique features. Yu Z, Derksen M, Te Pas BM, Ladstätter S, Overmeer R, Brazda P, van de Wetering M, Pourfarzad F, Vries RGJ, Megchelenbrink W, Bock C, Altucci L, Stunnenberg HG. Int J Cancer 157: 2025 2619-2634	1