RRBS data from TRACERx non-small cell lung cancer (NSCLC) tumours and matched normal adjacent tissue.

TRACERx (TRAcking Cancer Evolution through therapy (Rx)) is a prospective cohort study designed to investigate intratumor heterogeneity (ITH) in relation to clinical outcome, and to determine the clonal nature of driver events and evolutionary processes in early stage non-small cell lung cancer (NSCLC).

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001015534	TRACERx (TRAcking Cancer Evolution through therapy (Rx)) is a prospective cohort study designed to investigate intratumor heterogeneity (ITH) in relation to clinical outcome, and to determine the clonal nature of driver events and evolutionary processes in early stage non-small cell lung cancer (NSCLC).	Illumina HiSeq 2500 NextSeq 2000	124

Publications	Citations
DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution. Gimeno-Valiente F, Castignani C, Larose Cadieux E, Mensah NE, Liu X, Chen K, Chervova O, Karasaki T, Weeden CE, Richard C, Lai S, Martínez-Ruiz C, Lim EL, Frankell AM, Watkins TBK, Stavrou G, Usaite I, Lu WT, Marinelli D, Saghafinia S, Wilson GA, Dhami P, Vaikkinen H, Steif J, Veeriah S, Hynds RE, Hirst M, Hiley C, Feber A, Deniz Ö, Jamal-Hanjani M, McGranahan N, TRACERx Consortium, Beck S, Demeulemeester J, Tanić M, Swanton C, Van Loo P, Kanu N. Nat Genet 57: 2025 2226-2237	1

Publications

Citations

DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution.
Gimeno-Valiente F, Castignani C, Larose Cadieux E, Mensah NE, Liu X, Chen K, Chervova O, Karasaki T, Weeden CE, Richard C, Lai S, Martínez-Ruiz C, Lim EL, Frankell AM, Watkins TBK, Stavrou G, Usaite I, Lu WT, Marinelli D, Saghafinia S, Wilson GA, Dhami P, Vaikkinen H, Steif J, Veeriah S, Hynds RE, Hirst M, Hiley C, Feber A, Deniz Ö, Jamal-Hanjani M, McGranahan N, TRACERx Consortium, Beck S, Demeulemeester J, Tanić M, Swanton C, Van Loo P, Kanu N. Nat Genet 57: 2025 2226-2237