Genome-wide methylation profiling by high-throughput sequencing of tissue (resident) versus blood circulating memory T lymphocyte populations

This study contains RRBS data generated from 54 ex vivo samples, including CD4+ Trm (2x intestine, 2x lung, and 3x skin), CD4+CD69- tissue cells (2x bone marrow, 2x spleen, 2x intestine, 2x lung, and 3x skin), CD8+ Trm (2x bone marrow, 2x spleen, 2x intestine, 2x lung, and 3x skin), CD8+CD69- tissue cells (2x bone marrow, 2x spleen, 2x intestine, 2x lung, and 2x skin), blood CD4+ (7x) and CD8+ (8x) memory T cells.

Type: Epigenetics
Archiver: European Genome-Phenome Archive (EGA)

1 Publication

Publications	Citations
Methylomes of human CD4 and CD8 memory T lymphocytes reveal tissue-specific epigenetic signatures for maintenance and recall function. Deng X, Du W, Gasparoni G, Salhab A, Nordström K, Li J, Wagner V, Zhang E, Wachtlin J, Bodo J, Reinke S, Lei H, Perka C, Hardt S, Dörner T, Holmer C, Tönnies M, Bauer T, Chang HD, Polansky JK, Walter J, Durek P, Radbruch A, Dong J. Immun Inflamm 1: 2025 13	0