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Whole exome RNA sequencing of FFPE material from 49 pediatric BCP-LBL patients.

This study contain the results of whole exome-targeted transcriptome analyses of FFPE material from 49 pediatric B-cell precursor lymphoblastic lymphoma patients. Data are provided as Fastq files.

Type: Transcriptome Analysis
Archiver: European Genome-phenome Archive (EGA)

2 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000000419	In order to perform comprehensive transcriptomics and gene fusion analyses of a cohort of BCP-LBL patients, we performed RNA sequencing of 49 tissue samples from BCP-LBL patients. Because the material was available as FFPE, and had a relative low quality, we used a capture-based approach, where NGS libraries obtained from total RNA were captured in 4-plex, using a whole exome capture panel.	Illumina NovaSeq 6000	49
EGAD50000002047	In order to perform comprehensive transcriptomics and gene fusion analyses of a cohort of BCP-LBL and extramedullary (EM) manifestations of B-ALL patients, we performed RNA sequencing of 16 tissue samples from BCP-LBL and EM B-ALL patients. Because the material was available as FFPE, and had a relative low quality, we used a capture-based approach, where NGS libraries obtained from total RNA were captured in 4-plex, using a whole exome capture panel.	Illumina NovaSeq 6000	68

Publications	Citations
KMT2A-rearranged B-lymphoblastic lymphomas are skewed towards a more mature developmental stage. Iaccarino I, Hartmann AM, Yalcin F, Mondal M, Bozzetti C, Wolgast N, Loeffen JLC, Boer JM, Brüggemann M, Baldus CD, Cario G, Klapper W. Leukemia 40: 2026 1067-1071	0