Deciphering novel TCF4-driven mechanisms underlying a common triplet repeat expansion-mediated disease

short and long read data generated from cultured corneal endothelial cells (CECs) of unaffected controls, expansion positive Fuchs Endothelial Corneal Dystrophy (FECD) and expansion negative FECD individuals.

Type: RNASeq
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000000435	Long-read transcriptomic data of control and FECD exp positive CECs	Sequel	9
EGAD50000000436	Short-read transcriptomic data of unaffected control, expansion negative, and expansion positive FECD CECs	Illumina HiSeq 4000	10

Publications	Citations
Deciphering novel TCF4-driven mechanisms underlying a common triplet repeat expansion-mediated disease. Bhattacharyya N, Chai N, Hafford-Tear NJ, Sadan AN, Szabo A, Zarouchlioti C, Jedlickova J, Leung SK, Liao T, Dudakova L, Skalicka P, Parekh M, Moghul I, Jeffries AR, Cheetham ME, Muthusamy K, Hardcastle AJ, Pontikos N, Liskova P, Tuft SJ, Davidson AE. PLoS Genet 20: 2024 e1011230	1