ADARIO / Targeting ADAR1 in Immuno-Oncology

RNA editing analyses of BRCA-isogenic cell lines and patient-derived xenografts (PDX)

Type: Transcriptome Analysis
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000000739	RNA editing analyses of BRCA-isogenic cell lines and patient-derived xenografts (PDX)	Illumina NovaSeq X	22

Publications	Citations
Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers. Chabanon RM, Shcherbakova L, Lacroix-Triki M, Aglave M, Zeghondy J, Kriaa V, Gougé A, Garrido M, Edmond E, Bigot L, Krastev DB, Brough R, Pettitt SJ, Thomas-Bonafos T, Samstein R, Massard C, Deloger M, Tutt AN, Barlesi F, Loriot Y, Delaloge S, Tawk M, Degerny C, Lin YL, Pistilli B, Pasero P, Lord CJ, Postel-Vinay S. Nat Commun 16: 2025 6972	0

Publications

Citations

Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers.
Chabanon RM, Shcherbakova L, Lacroix-Triki M, Aglave M, Zeghondy J, Kriaa V, Gougé A, Garrido M, Edmond E, Bigot L, Krastev DB, Brough R, Pettitt SJ, Thomas-Bonafos T, Samstein R, Massard C, Deloger M, Tutt AN, Barlesi F, Loriot Y, Delaloge S, Tawk M, Degerny C, Lin YL, Pistilli B, Pasero P, Lord CJ, Postel-Vinay S. Nat Commun 16: 2025 6972