Exome-sequencing from monocytes (CD14pos), T-lymphocytes (CD3pos) and iGRAN (CD14neg) cells from CMML patients

Exome-sequencing from monocytes (CD14pos), T-lymphocytes (CD3pos) and iGRAN (CD14neg) cells from CMML patients [Publication title] CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia

Type: Exome Sequencing
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset

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Dataset ID	Description	Technology	Samples
EGAD50000000789	CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia [Abstract] In chronic myelomonocytic leukemia, blocking CXCL8 produced by clonal dysplastic granulocytes is a potential therapeutic strategy to slow disease progression. [Data provided] Exome-sequencing, bulk mRNA-seq and single-cell RNA-seq of iGRAN, monocytes and PBMC of CMML patients and controls.	Illumina HiSeq 2000 Illumina NovaSeq 6000	64