SAPCS Blood RNA-seq of prostate cancer patients

The study aims to quantify the gene expression in blood samples in 20 prostate cancer patients under the Southern African Prostate Cancer Study (SAPCS). The objective is to identify a list of differentially expressed genes.

Type: RNASeq
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000000982	Raw RNA-seq reads (FASTQ format) and Mapped sequencing reads (BAM format) of 20 Prostate cancer patients in Southern African Prostate Cancer Study (SAPCS). Each patient exhibit different pathogenic variations. The Illumina RNA-sequencing is performed from Blood extraction (from QIAamp RNA Blood Mini Kit). rRNA was removed prior using SortMeRNA. STAR aligner program was used for mapping to human genome GRCh38.p14, resulting in an average genome coverage of 9x.	unspecified	20

Publications	Citations
Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African men. Gong T, Jiang J, Uthayopas K, Bornman MSR, Gheybi K, Stricker PD, Weischenfeldt J, Mutambirwa SBA, Jaratlerdsiri W, Hayes VM. Nat Commun 16: 2025 2400	0