DNA sequencing of sgRNAs enriched from the CRISPR-Cas9 screened HCC organoids

Project aims to find enriched or depleted sgRNAs to identify functional genes in HCC progression and lenvatinib resistance

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000001240	DNA sequencing of sgRNAs in CRISPR-Cas9 screening and RNA sequencing of SF3B4-overexpressing liver organoids	Illumina NovaSeq 6000 Illumina NovaSeq X Sequel II	18

Publications	Citations
Genome-wide CRISPR screen identifies splicing factor SF3B4 in driving hepatocellular carcinoma. Guo Y, Xu M, Xue H, Ding X, Wong AM, Lin N, Pu D, Wong AM, Wang X, Zhao H, Wong N. Sci Adv 11: 2025 eadw7181	0