Effects of KSP inhibitor filanesib in aggressive hepatoblastoma PDX cells

Aim of this RNA sequencing dataset has been to asses effects caused by the KSP inhibitor filanesib in aggressive hepatoblastoma PDX cells. Two cell lines (HB-279 and HB-284) were utilised. DMSO-treated cells were used as controls.

Type: RNASeq
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000001314	This dataset contains RNA sequencing data of two hepatoblastoma PDX cell models. Cells were either treated with KSP inhibitor filanesib or with DMSO (controls).	unspecified	16

Publications	Citations
Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma. Nousiainen R, Eloranta K, Saarela J, Hassinen A, Luck TJ, Cairo S, Indersie E, Potdar S, Feodoroff MJ, Lohi J, Paavolainen L, Wilson DB, Pietiäinen V, Heikinheimo M, Pihlajoki M. NPJ Precis Oncol 9: 2025 122	1